422 21st Street, Denver, CO 80205 (MLS # 6487194)

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PRICE $1,250,000 dsIDX morgage calculator
BEDS 4
BATHS 2
HOME SIZE 6,565 sqft
LOT SIZE 6,099 sqft

Located in the heart of Five Points, this unique for-sale offering presents a compelling investment, owner-user, or redevelopment opportunity on a highly visible 6,270 SF corner lot just steps from Downtown Denver, Uptown, and the vibrant Five Points district. The property consists of a well-maintained single-family home and an adjacent office duplex, providing multiple income streams and flexible future potential. The approximately 2,565 SF single-family residence features four bedrooms and two bathrooms and is most recently operated as a successful Airbnb, offering immediate short-term rental income or the option for an owner-user residence. The office duplex is comprised of two office units of approximately 2,000 SF each, both tenant-occupied on month-to-month leases, allowing for steady income with near-term flexibility for repositioning or redevelopment. With its premier corner location, walkability to Denver's central business district, and proximity to restaurants, nightlife, transit, and cultural amenities, this property offers exceptional upside in one of Denver's most dynamic and rapidly evolving neighborhoods.

DAYS ON MARKET 9 LAST UPDATED 2/10/2026
TRACT Five Points YEAR BUILT 1886
COUNTY Denver STATUS Active
PROPERTY TYPE(S) Single Family

SCHOOLS
Elementary School Whittier E-8
Jr. High School Cole Arts And Science Academy
High School East


ADDITIONAL DETAILS
AIR None
CONSTRUCTION Brick
HEAT Hot Water
LOT 6098 sq ft
LOT DESCRIPTION Level
SEWER Public Sewer
STORIES 2
SUBDIVISION Five Points
TAXES 15636
MORTGAGE CALCULATOR
   

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Listing provided by Karen Zeile, Kentwood Commercial, Llc
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